Acidic drinking water and risk of childhood-onset type 1 diabetes.

Birth Weight and Childhood Onset Type 1 Diabetes: A Case-Control Study in Shiraz, South of Iran

To determine the relation between birth weight and age of presentation of type 1 diabetes and assess its risk factors, a case-control study was done on all diabetic patients under the age of 15, who were registered in Shiraz Diabetic Center or admitted in Namazi Hospital. A case group of 87 diabetic patients were matched with a control group of 100 healthy individuals. Birth weight ≥ 4kg was de...

Does the risk of childhood diabetes mellitus require revision of the guideline values for nitrate in drinking water?

In recent years, several studies have addressed a possible relationship between nitrate exposure and childhood type 1 insulin-dependent diabetes mellitus. The present ecologic study describes a possible relation between the incidence of type 1 diabetes and nitrate levels in drinking water in The Netherlands, and evaluates whether the World Health Organization and the European Commission standar...

Nitrate in Drinking Water and Childhood-onset Insulin-dependent Diabetes Mellitus in Scotland and Central England

pH of Drinking Water Influences the Composition of Gut Microbiome and Type 1 Diabetes Incidence

Nonobese diabetic (NOD) mice spontaneously develop type 1 diabetes (T1D), progression of which is similar to that in humans, and therefore are widely used as a model for understanding the immunological basis of this disease. The incidence of T1D in NOD mice is influenced by the degree of cleanliness of the mouse colony and the gut microflora. In this report, we show that the T1D incidence and r...

Preventive effect of natural dietary supplement -Flavin7- on the onset of spontaneous diabetes mellitus in bio-breeding diabetes prone rats

Introduction: The aim of the present study was to evaluate the preventive effects of Flavin7 in prediabetic bio-breeding diabetes prone (BB-DP) rats. Methods: Foutthy rats were divided into 2 equal groups: group C (untreated control group) and group F7 with Flavin7 (natural dietary supplement F7 with bioflavonoids, 0.2 mg/l) in drinking water from 21st day after birth to 171st day of their ...